Impact of brief prewarming on anesthesia-related core-temperature drop, hemodynamics, microperfusion and postoperative ventilation in cytoreductive surgery of ovarian cancer: a randomized trial.

ABSTRACT:

Background

General (GA)- and epidural-anesthesia may cause a drop in body-core-temperature (BCT_drop), and hypothermia, which may alter tissue oxygenation (StO₂) and microperfusion after cytoreductive surgery for ovarian cancer. Cell metabolism of subcutaneous fat- or skeletal muscle cells, measured in microdialysis, may be affected. We hypothesized that forced-air prewarming during epidural catheter placement and induction of GA maintains normothermia and improves microperfusion.

Methods

After ethics approval 47 women scheduled for cytoreductive surgery were prospectively enrolled. Women in the study group were treated with a prewarming of 43 °C during epidural catheter placement. BCT (Spot on®, 3 M) was measured before (T₁), after induction

SUBMITTER: Kaufner L 

PROVIDER: S-EPMC6706928 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature