Severity of Desaturations Reflects OSA-Related Daytime Sleepiness Better Than AHI.

ABSTRACT: STUDY OBJECTIVES:The aim was to investigate how the severity of apneas, hypopneas, and related desaturations is associated with obstructive sleep apnea (OSA)-related daytime sleepiness. METHODS:Multiple Sleep Latency Tests and polysomnographic recordings of 362 patients with OSA were retrospectively analyzed and novel diagnostic parameters (eg, obstruction severity and desaturation severity), incorporating severity of apneas, hypopneas, and desaturations, were computed. Conventional statistical analysis and multivariate analyses were utilized to investigate connection of apnea-hypopnea index (AHI), oxygen desaturation index (ODI), conventional hypoxemia parameters, and novel diagnostic parameters with mean daytime sleep latency (MSL). RESULTS:In the whole population, 10% increase in values

SUBMITTER: Kainulainen S 

PROVIDER: S-EPMC6707054 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature