Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit.

ABSTRACT:

Importance

A high Pao2, termed hyperoxemia, is postulated to have deleterious health outcomes. To date, the association between hyperoxemia during the ongoing management of critical illness and mortality has been incompletely evaluated in children.

Objective

To examine whether severe hyperoxemia events are associated with mortality among patients admitted to a pediatric intensive care unit (PICU).

Design, setting, and participants

A retrospective cohort study was conducted over a 10-year period (January 1, 2009, to December 31, 2018); all 23 719 PICU encounters at a quaternary children's hospital with a documented arterial blood gas measurement were evaluated.

Exposures

Severe hyperoxemia, defined as Pao2 level greater than or equal to 300 mm Hg (40 kPa).

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SUBMITTER: Ramgopal S 

PROVIDER: S-EPMC6707098 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature