Systemic inflammation score in locally advanced rectal cancer patients following total mesorectal excision.

ABSTRACT:

Objective

The objective of the study was to evaluate whether any association exists between systemic inflammation score (SIS) and adverse events (AEs) and survival of locally advanced rectal cancer patients treated with total mesorectal excision (TME) followed by adjuvant chemoradiotherapy.

Patients and methods

All of the 109 rectal cancer patients recruited between May 2008 and June 2015 were treated with TME followed by adjuvant chemoradiotherapy. The prognostic ability of SIS for overall survival (OS) was calculated by the receiver operating characteristic (ROC) curves.

Results

According to the classification of the SIS, 22 (20.2%), 59 (54.1%) and 28 (25.7%) patients were classified as a score of 2, 1 and 0, respectively. With an area under the curve (AUC) of 0.616

SUBMITTER: Feng Y 

PROVIDER: S-EPMC6707432 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature