A Systematic Scoping Review of Surgically Manipulated Adipose Tissue and the Regulation of Energetics and Body Fat in Animals.

ABSTRACT:

Objective

Surgical manipulations of adipose tissue by removal, or partial lipectomy, have demonstrated body fat compensation and recovered body weight, suggesting that the body is able to resist changes to body composition. However, the mechanisms underlying these observations are not well understood. The purpose of this scoping review is to provide an update on what is currently known about the regulation of energetics and body fat after surgical manipulations of adipose tissue in small mammals.

Methods

PubMed and Scopus were searched to identify 64 eligible studies. Outcome measures included body fat, body weight, food intake, and circulating biomarkers.

Results

Surgeries performed included lipectomy (72%) or transplantation (12%) in mice (35%), rats (35%), and othe

SUBMITTER: Murillo AL 

PROVIDER: S-EPMC6707830 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature