Regulation of rumen development in neonatal ruminants through microbial metagenomes and host transcriptomes.

ABSTRACT:

Background

In ruminants, early rumen development is vital for efficient fermentation that converts plant materials to human edible food such as milk and meat. Here, we investigate the extent and functional basis of host-microbial interactions regulating rumen development during the first 6 weeks of life.

Results

The use of microbial metagenomics, together with quantification of volatile fatty acids (VFAs) and qPCR, reveals the colonization of an active bacterial community in the rumen at birth. Colonization of active complex carbohydrate fermenters and archaea with methyl-coenzyme M reductase activity was also observed from the first week of life in the absence of a solid diet. Integrating microbial metagenomics and host transcriptomics reveals only 26.3% of mRNA transcripts

SUBMITTER: Malmuthuge N 

PROVIDER: S-EPMC6708143 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature