Thyroid hormone levels associate with exposure to polychlorinated biphenyls and polybrominated biphenyls in adults exposed as children.

ABSTRACT:

Background

Michigan residents were directly exposed to endocrine-disrupting compounds, polybrominated biphenyl (PBB) and polychlorinated biphenyl (PCB). A growing body of evidence suggests that exposure to certain endocrine-disrupting compounds may affect thyroid function, especially in people exposed as children, but there are conflicting observations. In this study, we extend previous work by examining age of exposure's effect on the relationship between PBB exposure and thyroid function in a large group of individuals exposed to PBB.

Methods

Linear regression models were used to test the association between serum measures of thyroid function (total thyroxine (T₄), total triiodothyronine (T₃), free T₄, free T₃, thyroid stimulatin

SUBMITTER: Curtis SW 

PROVIDER: S-EPMC6708149 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature