Antimicrobial susceptibility and molecular characteristics of Mycoplasma pneumoniae isolates across different regions of China.

ABSTRACT:

Background

In China mainland, most Mycoplasma pneumoniae related studies are carried out in Beijing and Shanghai, while rare studies are performed in the other regions. In this study, we analyzed the molecular biology characteristics and antimicrobial susceptibility of clinical isolates of M. pneumoniae from 5 regions between January 2017 and December 2018.

Methods

Genotyping was performed to 154 M. pneumoniae isolates from 5 cities using PCR and multiple-locus variable-number tandem repeat analysis (MLVA) method. Antimicrobial susceptibility test was performed to all the isolates against 4 antibiotics. Sequencing was performed to the amplification products of the 23S rRNA drug resistant gene.

Results

Genotype I was detected in 118 M. pneumonia

SUBMITTER: Zhao F 

PROVIDER: S-EPMC6708159 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature