Sudden-Onset Sensorineural Hearing Loss after Immunization: A Case-Centered Analysis.

ABSTRACT:

Objective

Case reports of sudden sensorineural hearing loss (SSHL) following vaccines have led to concerns that vaccines may rarely cause hearing loss. Because of this concern, we analyzed for an association between SSHL and vaccinations.

Study design

We used a case-centered method, equivalent to a case control design using immunization dates from all matched members of the population to calculate exposure to vaccines, rather than sampling.

Setting

Kaiser Permanente Northern California (KPNC), 2007 to 2013.

Subjects and methods

We searched KPNC databases from 2007 to 2013 for all first-time diagnoses of SSHL. We used the date of any hearing- or ear-related visit in the 60 days prior to the first SSHL diagnosis as the onset date. Using only SSHL cases immunized

SUBMITTER: Baxter R 

PROVIDER: S-EPMC6708600 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature