Optimal treatment for spermatogenesis in male patients with hypogonadotropic hypogonadism.

ABSTRACT:

Background

To compare the efficacies of gonadotropin-releasing hormone (GnRH) pulse subcutaneous infusion with combined human chorionic gonadotropin and human menopausal gonadotropin (HCG/HMG) intramuscular injection have been performed to treat male hypogonadotropic hypogonadism (HH) spermatogenesis.

Methods

In total, 220 idiopathic/isolated HH patients were divided into the GnRH pulse therapy and HCG/HMG combined treatment groups (n = 103 and n = 117, respectively). The luteinizing hormone and follicle-stimulating hormone levels were monitored in the groups for the 1st week and monthly, as were the serum total testosterone level, testicular volume and spermatogenesis rate in monthly follow-up sessions.

Results

In the GnRH group and HCG/HMG group, the testosterone le

SUBMITTER: Lin J 

PROVIDER: S-EPMC6709243 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature