Impact of intracoronary contrast injection pressure on reperfusion during primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction: A prospective randomized pilot study.

ABSTRACT:

Background

Distal embolization of plaque and thrombotic debris in the infarct-related artery (IRA) may lead to microvascular obstruction resulting in impaired myocardial reperfusion.The aim of the study was to assess the impact of contrast injection pressure in IRA, during primary percutaneous coronary intervention (PCI), on myocardial reperfusion in patients with acute ST-segment elevation myocardial infarction (STEMI).

Methods

This prospective, randomized, open label, pilot trial evaluated acute STEMI patients who underwent primary PCI, with blinded evaluation of end points. Patients were assigned to higher injection pressure group A (550 pound/inch²) or lower injection pressure group B (200 pound/inch²). Primary endpoint was the postprocedural incide

SUBMITTER: Stambuk K 

PROVIDER: S-EPMC6709366 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature