A 20-year multicenter analysis of dialysis-dependent patients who had aortic or mitral valve replacement: Implications for valve selection.

ABSTRACT:

Objective

Valve selection in dialysis-dependent patients can be difficult because long-term survival is diminished and bleeding risks during anticoagulation treatment are greater in patients with renal failure. In this study we analyzed long-term outcomes of dialysis-dependent patients who underwent valve replacement to help guide optimal prosthetic valve type selection.

Methods

Dialysis-dependent patients who underwent aortic and/or mitral valve replacement at 3 institutions over 20 years were examined. The primary outcome was long-term survival. A Cox regression model was used to estimate survival according to 5 ages, presence of diabetes, and/or heart failure symptoms.

Results

Four hundred twenty-three available patients were analyzed; 341 patients had biological a

SUBMITTER: Manghelli JL 

PROVIDER: S-EPMC6709586 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature