Temporal Trends Associated With the Rise in Alcoholic Liver Disease-related Liver Transplantation in the United States.

ABSTRACT:

Background

In the United States, alcoholic liver disease (ALD) has recently become the leading indication for liver transplantation.

Methods

Using the United Network for Organ Sharing registry, we examined temporal trends in adult liver transplant waitlist (WL) registrants and recipients with chronic liver disease (CLD) due to ALD from 2007 to 2016.

Results

From 2007 to 2016, ALD accounted for 20.4% (18 399) of all CLD WL additions. The age-standardized ALD WL addition rate was 0.459 per 100 000 US population in 2007; nearly doubled to 0.872 per 100 000 US population in 2016 and increased with an average annual percent change of 47.56% (95% confidence interval, 30.33% to 64.72%).The ALD WL addition rate increased over twofold among young (18-39 years) and middle-aged

SUBMITTER: Cholankeril G 

PROVIDER: S-EPMC6709987 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature