Genetic and environmental architecture of processing speed across midlife.

ABSTRACT:

Objective

Processing Speed (PS) is an important domain in cognitive aging that is characterized by multiple related but nonidentical abilities. Few studies have directly investigated the relationships among PS measures, and none have used genetically informed methods. In this study, we examined the relationship between measures of PS at up to two time points during middle age.

Method

We examined data from 1,262 middle-aged men when the sample was at a mean age of 56 and a mean age 62 years. Participants completed 6 measures of PS from three different cognitive tests. We used a genetically informative, confirmatory factor analytic approach to evaluate the phenotypic and genetic relationships cross-sectionally at both single time points and across time.

Results

A higher

SUBMITTER: Sanderson-Cimino M 

PROVIDER: S-EPMC6710143 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature