Prenatal exposure to nitrate in drinking water and the risk of congenital anomalies.

ABSTRACT:

Background

Nitrate is a common water contaminant that has been associated with birth defects, although the evidence is limited. The purpose of this study was to examine whether maternal consumption of nitrate through drinking water is associated with an increased risk of congenital anomalies.

Methods

The study included a total of 348,250 singletons births from the state of Missouri between January 1, 2004 and December 31, 2008. Individual-level birth defect data and maternal and child characteristics were obtained from the Missouri birth defects registry and state vital statistics records. Outcomes were linked with county-specific monthly estimates of the nitrate concentration in finished water, based on data collected for compliance with the Safe Drinking Water Standard. Po

SUBMITTER: Blaisdell J 

PROVIDER: S-EPMC6710151 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature