Stressors in Midlife and Risk of Dementia: The Role of Race and Education.

ABSTRACT:

Background

Posttraumatic stress disorder is associated with increased dementia risk but less is known about stress because of everyday problems in diverse populations.

Methods

A total of 9605 health care plan members who provided information regarding midlife stressors in 1972 to 1973 (ages, 40 to 55 y) were followed for dementia diagnosis between 1996 and 2017. Cox proportional hazard models evaluated associations between midlife stressors and dementia adjusting for demographics and lifecourse health indicators.

Results

Reporting at least 1 midlife stressor was associated with 17% greater dementia risk [hazard ratio (HR), 1.17; 95% confidence interval (CI),1.07-1.27] versus 0 midlife stressors and 26% increased risk among those with less than equal to high school edu

SUBMITTER: Gilsanz P 

PROVIDER: S-EPMC6710152 | biostudies-literature | 2019 Jul-Sep

REPOSITORIES: biostudies-literature