Serious cardiac complications in coronary spasm provocation tests using acetylcholine or ergonovine: analysis of 21 512 patients from the diagnosis procedure combination database in Japan.

ABSTRACT:

Background

Previous studies on complications with coronary spasm provocation tests were based on small sample sizes or were limited to high-volume centers. The risk of provocation tests using acetylcholine (ACH) or ergonovine (ER) remains to be fully examined by a large-scale multicenter study.

Hypothesis

ACH provocation tests are associated with a higher rate of serious cardiac complications than ER tests.

Methods

Using the Diagnosis Procedure Combination database in Japan, we identified patients aged ≥20 years who underwent a pharmacological provocation test during coronary angiography. We assessed the composite outcome of cardiac complications requiring urgent procedures (defibrillation, chest compression, intra-aortic balloon pumping, or extracorporeal membrane ox

SUBMITTER: Isogai T 

PROVIDER: S-EPMC6711001 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature