Role of dynamic contrast-enhanced MRI in evaluating the association between contralateral parenchymal enhancement and survival outcome in ER-positive, HER2-negative, node-negative invasive breast cancer.

ABSTRACT:

Background

Background parenchymal enhancement (BPE) on dynamic contrast-enhanced (DCE)-MRI has been associated with breast cancer risk, both based on qualitative and quantitative assessments.

Purpose

To investigate whether BPE of the contralateral breast on preoperative DCE-MRI is associated with therapy outcome in ER-positive, HER2-negative, node-negative invasive breast cancer.

Study type

Retrospective.

Population

In all, 289 patients with unilateral ER-positive, HER2-negative, node-negative breast cancer larger than 5 mm.

Field strength/sequence

3T, T₁ -weighted DCE sequence.

Assessment

BPE of the contralateral breast was assessed qualitatively by two dedicated radiologists and quantitatively (using region-of-interest and automatic b

SUBMITTER: Shin GW 

PROVIDER: S-EPMC6711368 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature