Staging of nutrition disorders in non-small-cell lung cancer patients: utility of skeletal muscle mass assessment.

ABSTRACT:

Background

An international consensus proposed in 2011 a definition and classification system for cachexia (CAX), mainly based on weight loss, sarcopenia [skeletal muscle mass (SMM) loss], inflammation, and anorexia. The aim of this study was to stage CAX in non-small-cell lung cancer (NSCLC) patients by using a classification based on the Fearon criteria and supported by quantifiable parameters.

Methods

This was a cross-sectional and non-interventional multicentre study. SMM was assessed by analysing L3 computed tomography-scan images. Patients completed the anorexia/CAX subscale of the Functional Assessment of Anorexia/Cachexia Therapy, EORTC QLQ-C30 quality of life (QoL) and International Physical Activity Questionnaire (IPAQ).

Results

Patients were recruited in 56

SUBMITTER: Antoun S 

PROVIDER: S-EPMC6711412 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature