Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.

ABSTRACT:

Background

Early mobilization improves physical independency of critically ill patients at hospital discharge in a general intensive care unit (ICU)-cohort. We aimed to investigate clinical and molecular benefits or detriments of early mobilization and muscle activating measures in a high-risk ICU-acquired weakness cohort.

Methods

Fifty patients with a SOFA score ≥9 within 72 h after ICU admission were randomized to muscle activating measures such as neuromuscular electrical stimulation or whole-body vibration in addition to early protocol-based physiotherapy (intervention) or early protocol-based physiotherapy alone (control). Muscle strength and function were assessed by Medical Research Council (MRC) score, handgrip strength and Functional Independence Measure at first aw

SUBMITTER: Wollersheim T 

PROVIDER: S-EPMC6711421 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature