Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery.

ABSTRACT:

Background

Body composition assessment, measured using single-slice computed tomography (CT) image at L3 level, and aerobic physical fitness, objectively measured using cardiopulmonary exercise testing (CPET), are each independently used for perioperative risk assessment. Sarcopenia (i.e. low skeletal muscle mass), myosteatosis [i.e. low skeletal muscle radiation attenuation (SM-RA)], and impaired objectively measured aerobic fitness (reduced oxygen uptake) have been associated with poor post-operative outcomes and survival in various cancer types. However, the association between CT body composition and physical fitness has not been explored. In this study, we assessed the association of CT body composition with selected CPET variables in patients undergoing hepatobiliary and panc

SUBMITTER: West MA 

PROVIDER: S-EPMC6711456 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature