Resting-state and Vocabulary Tasks Distinctively Inform On Age-Related Differences in the Functional Brain Connectome.

ABSTRACT: Most of the current knowledge about age-related differences in brain neurofunctional organization stems from neuroimaging studies using either a "resting state" paradigm, or cognitive tasks for which performance decreases with age. However, it remains to be known if comparable age-related differences are found when participants engage in cognitive activities for which performance is maintained with age, such as vocabulary knowledge tasks. A functional connectivity analysis was performed on 286 adults ranging from 18 to 80 years old, based either on a resting state paradigm or when engaged in vocabulary tasks. Notable increases in connectivity of regions of the language network were observed during task completion. Conversely, only age-related decreases were observed across the whole connec

SUBMITTER: Ferre P 

PROVIDER: S-EPMC6711486 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature