Eye Degeneration and Loss of otx5b Expression in the Cavefish Sinocyclocheilus tileihornes.

ABSTRACT: Cave animals possess remarkable phenotypes associated with existence in their dark environments. The Chinese cavefish Sinocyclocheilus tileihornes shows substantial eye degeneration, a trait shared by most cave species. The extent to which independent evolution of troglomorphic traits uses convergent molecular genetic mechanisms is as yet unknown. We performed transcriptome-wide gene expression profiling in S. tileihornes eyes and compared results with those from the closely related surface species S. angustiporus and an independently derived congeneric cavefish, S. anophthalmus. In total, 52.85 million 100 bp long paired-end clean reads were generated for S. tileihornes, and we identified differentially expressed genes between the three possible pairs of species. Functional analysis of ge

SUBMITTER: Huang Z 

PROVIDER: S-EPMC6711879 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature