The Association Between Polypharmacy and Physical Function in Older Adults: a Systematic Review.

ABSTRACT:

Background

Reduced physical function and polypharmacy (PPha) are two highly prevalent negative effects of aging, which are expected to increase more, since demographic aging is expected to grow rapidly within the next decades. Previous research suggests that polypharmacy (PPha) is a predictor of poor physical function and vice versa in older adults and therefore we conducted a systematic review of the literature to summarize and critically analyze the relationship between physical function and PPha and vice versa in older adults, in order to provide recent scientific evidence.

Methods

We searched MEDLINE and Embase from their inception to 19th October 2018 for English-language observational studies or trials assessing the effect of PPha on physical function and vice versa in

SUBMITTER: Katsimpris A 

PROVIDER: S-EPMC6712133 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature