The Protective Effects of Increasing Serum Uric Acid Level on Development of Metabolic Syndrome.

ABSTRACT: BACKGROUND:It has not been determined whether changes in serum uric acid (SUA) level are associated with incident metabolic syndrome (MetS). The aim of the current study was to investigate the relationship between changes in SUA level and development of MetS in a large number of subjects. METHODS:In total, 13,057 subjects participating in a medical health check-up program without a diagnosis of MetS at baseline were enrolled. Cox proportional hazards models were used to test the independent association of percent changes in SUA level with development of MetS. RESULTS:After adjustment for age, systolic blood pressure, body mass index, fat-free mass (%), estimated glomerular filtration rate, smoking status, fasting glucose, triglyceride, low density lipoprotein cholesterol, high density lipo

SUBMITTER: Yu TY 

PROVIDER: S-EPMC6712225 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature