Predictive value of a series of inflammatory markers in COPD for lung cancer diagnosis: a case-control study.

ABSTRACT:

Background

There is a relationship between Chronic Obstructive Pulmonary Disease (COPD) and the development of lung cancer (LC). The aim of this study is to analyse several blood markers and compare their concentrations in patients with only COPD and LC + COPD.

Methods

Case-control study with cases presenting combined LC and COPD and two control groups (patients presenting only COPD and patients presenting only LC). We also included LC patients with descriptive purposes. In both groups, peripheral blood analyses of TNF-α, IL-6, IL-8, total leukocyte, lymphocyte and neutrophil counts, neutrophil-to-lymphocyte ratio, total platelet count, mean platelet volume, platelet-to-lymphocyte ratio, alpha 1-antitripsin (A1AT), IgE, C-reactive protein, fibrinogen, cholesterol and bilirub

SUBMITTER: Mouronte-Roibas C 

PROVIDER: S-EPMC6712782 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature