Effect of delayed misoprostol dosing interval for induction of labor: a retrospective study.

ABSTRACT:

Background

Induction of labor occurs in greater than 22% of all pregnancies in the United States. Previous studies have shown that misoprostol is more effective for induction than oxytocin or dinoprostone alone. The World Health Organization recommends vaginal misoprostol 25mcg every 6 hours and the American Congress of Obstetricians and Gynecologists recommends 25mcg vaginal misoprostol every three to 6 hours. Although route of administration and dosage of misoprostol has been extensively studied, little is known about the optimal dosing interval of vaginal misoprostol.

Methods

The primary objective of this study is to determine the effect of delayed vaginal misoprostol dosing, defined as any interval longer than 4.5 h, on time to vaginal delivery. Our hypothesis is that th

SUBMITTER: Harman Crowell EH 

PROVIDER: S-EPMC6712846 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature