Ischemic core thresholds change with time to reperfusion: A case control study.

ABSTRACT:

Introduction

We aimed to identify whether acute ischemic stroke patients with known complete reperfusion after thrombectomy had the same baseline computed tomography perfusion (CTP) ischemic core threshold to predict infarction as thrombolysis patients with complete reperfusion.

Methods

Patients who underwent thrombectomy were matched by age, clinical severity, occlusion location, and baseline perfusion lesion volume to patients who were treated with intravenous alteplase alone from the International Stroke Perfusion Imaging Registry. A pixel-based analysis of coregistered pretreatment CTP and 24-hour diffusion-weighted imaging (DWI) was then undertaken to define the optimum CTP thresholds for the ischemic core.

Results

There were 132 eligible thrombectomy patients an

SUBMITTER: Bivard A 

PROVIDER: S-EPMC6712948 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature