Ontology highlight
ABSTRACT:
SUBMITTER: Urbiola C
PROVIDER: S-EPMC6712949 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Urbiola Carles C Santer Frédéric R FR Petersson Monika M van der Pluijm Gabri G Horninger Wolfgang W Erlmann Patrik P Wollmann Guido G Kimpel Janine J Culig Zoran Z von Laer Dorothee D
International journal of cancer 20180703 7
Oncolytic viruses, including the oncolytic rhabdovirus VSV-GP tested here, selectively infect and kill cancer cells and are a promising new therapeutic modality. Our aim was to study the efficacy of VSV-GP, a vesicular stomatitis virus carrying the glycoprotein of lymphocytic choriomeningitis virus, against prostate cancer, for which current treatment options still fail to cure metastatic disease. VSV-GP was found to infect 6 of 7 prostate cancer cell lines with great efficacy. However, suscepti ...[more]