Neuropsychological function at first episode in treatment-resistant psychosis: findings from the ÆSOP-10 study.

ABSTRACT:

Background

Neuropsychological investigations can help untangle the aetiological and phenomenological heterogeneity of schizophrenia but have scarcely been employed in the context of treatment-resistant (TR) schizophrenia. No population-based study has examined neuropsychological function in the first-episode of TR psychosis.

Methods

We report baseline neuropsychological findings from a longitudinal, population-based study of first-episode psychosis, which followed up cases from index admission to 10 years. At the 10-year follow up patients were classified as treatment responsive or TR after reconstructing their entire case histories. Of 145 cases with neuropsychological data at baseline, 113 were classified as treatment responsive, and 32 as TR at the 10-year follow-up.

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SUBMITTER: Kravariti E 

PROVIDER: S-EPMC6712950 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature