Impact of race/ethnicity on insulin resistance and hypertriglyceridaemia.

ABSTRACT:

Objective

Insulin sensitivity affects plasma triglyceride concentration and both differ by race/ethnicity. The purpose of this study was to provide a comprehensive assessment of the variation in insulin sensitivity and its relationship to hypertriglyceridaemia between five race/ethnic groups.

Research design and methods

In this cross-sectional study, clinical data for 1025 healthy non-Hispanic White, Hispanic White, East Asian, South Asian and African American individuals were analysed. Insulin-mediated glucose disposal (a direct measure of peripheral insulin sensitivity) was measured using the modified insulin suppression test. Statistical analysis was performed using analysis of co-variance.

Results

Of the study participants, 63% were non-Hispanic White, 9% were His

SUBMITTER: Raygor V 

PROVIDER: S-EPMC6713231 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature