Birth weight discordance in very low birth weight twins: mortality, morbidity, and neurodevelopment.

ABSTRACT:

Objective

Examine outcomes among birth weight concordant and discordant 401-1500 g twins.

Study design

Twins (n = 8,114) at NICHD Neonatal Research Network (1994-2011) were studied. Discordance (birth weight difference/larger twin birth weight x 100%) was categorized into: ≤ 14, > 14-20, > 20-30, and > 30%. Separate logistic regression models for the smaller and larger infants assessed the adjusted association between discordance and outcomes.

Results

Compared with the smaller twin with ≤ 14% discordance, mortality, necrotizing enterocolitis, severe retinopathy of prematurity, bronchopulmonary dysplasia, and neurodevelopmental impairment or death were highest among the smaller twins with discordance > 30%. The larger twins with discordance > 30% had higher odds of pat

SUBMITTER: Boghossian NS 

PROVIDER: S-EPMC6713585 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature