Glaucoma incidence risk in a cohort of Mayak PA workers occupationally exposed to ionizing radiation.

ABSTRACT: Glaucoma is a major cause of visual impairment, and secondary glaucoma manifested as neovascular glaucoma has long been known to occur following high-dose fractionated radiation therapy. In contrast, little is known as to whether ionizing radiation exposure causes primary glaucoma, except that a single study in Japanese atomic bomb survivors has reported a significantly increase risk. Therefore, the effect of lower dose and lower dose rate remains unclear. Here we report that in Russian Mayak Production Association workers occupationally exposed to chronic radiation for prolonged periods, incidence of total primary glaucoma and primary open-angle glaucoma is significantly associated with various non-radiation factors (sex, attained age, and cataract diagnosed prior to glaucoma), but neithe

SUBMITTER: Bragin EV 

PROVIDER: S-EPMC6713741 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature