Metabolites-Enabled Survival of Crucian Carps Infected by Edwardsiella tarda in High Water Temperature.

ABSTRACT: Temperature is one of the major factors that affect the outbreak of infectious disease. Lines of evidences have shown that virulence factors can be controlled by thermo-sensors in bacterial pathogens. However, how temperature influences host's responses to the pathogen is still largely unexplored, and the study of this might pave the way to develop strategies to manage pathogenic bacterial infection. In the present study, we show that finfish Carassius carassius, the crucian carp that is tolerant to a wide range of temperatures, is less susceptible to bacterial infection when grown in 20°C than in 30°C. The different responses of C. carassius to bacterial infection could be partially explained by the distinct metabolisms under the specific temperatures: C. carassius shows elevated tricarbo

SUBMITTER: Jiang M 

PROVIDER: S-EPMC6713922 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature