Altered Functional Connectivity in Patients With Sloping Sensorineural Hearing Loss.

ABSTRACT:

Background

Sensory deprivation, such as hearing loss, has been demonstrated to change the intrinsic functional connectivity (FC) of the brain, as measured with resting-state functional magnetic resonance imaging (rs-fMRI). Patients with sloping sensorineural hearing loss (SNHL) are a unique population among the hearing impaired, as they have all been exposed to some auditory input throughout their lifespan and all use spoken language.

Materials and methods

Twenty patients with SNHL and 21 control subjects participated in a rs-fMRI study. Whole-brain seed-driven FC maps were obtained, with audiological scores of patients, including hearing loss severity and speech performance, used as covariates.

Results

Most profound differences in FC were found between patients with

SUBMITTER: Wolak T 

PROVIDER: S-EPMC6713935 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature