Differential transcriptome dynamics during the onset of conceptus elongation and between female and male porcine embryos.

ABSTRACT:

Background

Porcine embryos undergo rapid differentiation and expansion between Days 8 and 12 before attaching to the maternal uterine epithelial surface after Day 13. It is known that maternal recognition of pregnancy and successful implantation are driven by mutual interactions between the elongated conceptus and the maternal endometrium. While most of the genes involved in regulation of embryo development are located on autosomal chromosomes, gene expression on sex chromosomes is modulating development through sex-specific transcription. To gain more insights into the dynamic transcriptome of preimplantation embryos at the onset of elongation and into X-linked gene expression, RNA-seq analyses were performed for single female and male porcine embryos collected on Days 8, 10, and

SUBMITTER: Zeng S 

PROVIDER: S-EPMC6714402 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature