Comparative and functional genomics of the protozoan parasite Babesia divergens highlighting the invasion and egress processes.

ABSTRACT: Babesiosis is considered an emerging disease because its incidence has significantly increased in the last 30 years, providing evidence of the expanding range of this rare but potentially life-threatening zoonotic disease. Babesia divergens is a causative agent of babesiosis in humans and cattle in Europe. The recently sequenced genome of B. divergens revealed over 3,741 protein coding-genes and the 10.7-Mb high-quality draft become the first reference tool to study the genome structure of B. divergens. Now, by exploiting this sequence data and using new computational tools and assembly strategies, we have significantly improved the quality of the B. divergens genome. The new assembly shows better continuity and has a higher correspondence to B. bovis chromosomes. Moreover, we present a di

SUBMITTER: Gonzalez LM 

PROVIDER: S-EPMC6715253 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature