Effect of coexisting vascular disease on long-term risk of recurrent events after TIA or stroke.

ABSTRACT:

Objective

To determine whether patients with TIA or ischemic stroke with coexisting cardiovascular disease (i.e., history of coronary or peripheral artery disease) are still at high risk of recurrent ischemic events despite current secondary prevention guidelines.

Methods

In a population-based study in Oxfordshire, UK (Oxford Vascular Study), we studied consecutive patients with TIA or ischemic stroke for 2002-2014. Patients were treated according to current secondary prevention guidelines and we determined risks of coronary events, recurrent ischemic stroke, and major bleeding stratified by the presence of coexisting cardiovascular disease.

Results

Among 2,555 patients (9,148 patient-years of follow-up), those (n = 640; 25.0%) with coexisting cardiovascular disease (

SUBMITTER: Boulanger M 

PROVIDER: S-EPMC6715511 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature