Early Brain Injury After Poor-Grade Subarachnoid Hemorrhage.

ABSTRACT:

Purpose of review

Over the last years, the focus of clinical and animal research in subarachnoid hemorrhage (SAH) shifted towards the early phase after the bleeding based on the association of the early injury pattern (first 72 h) with secondary complications and poor outcome. This phase is commonly referenced as early brain injury (EBI). In this clinical review, we intended to overview commonly used definitions of EBI, underlying mechanisms, and potential treatment implications.

Recent findings

We found a large heterogeneity in the definition used for EBI comprising clinical symptoms, neuroimaging parameters, and advanced neuromonitoring techniques. Although specific treatments are currently not available, therapeutic interventions are aimed at ameliorating EBI by improving

SUBMITTER: Rass V 

PROVIDER: S-EPMC6715808 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature