The Epidemiology of Antiphospholipid Syndrome: A Population-Based Study.

ABSTRACT:

Objective

To estimate the annual incidence and prevalence of and frequency of mortality associated with antiphospholipid syndrome (APS).

Methods

An inception cohort of patients with incident APS in 2000-2015 from a geographically well-defined population was identified based on comprehensive individual medical records review. All cases met the 2006 Sydney criteria for APS (primary definition) or had a diagnosis of APS confirmed by physician consensus (secondary definition). Levels of lupus anticoagulant, IgM and IgG anticardiolipin antibodies, and anti-β2-glycoprotein I antibodies were tested in a centralized laboratory. Incidence rates were age- and sex-adjusted to the 2010 US white population. Prevalence estimates were obtained from the incidence rates, assuming that there

SUBMITTER: Duarte-Garcia A 

PROVIDER: S-EPMC6717037 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature