Perceptions of using lithium in fracture management: a survey of orthopaedic surgeons, fracture patients and the general public.

ABSTRACT:

Background

Lithium, an established psychiatric medication, has recently been shown to enhance new bone formation in preclinical fracture models. Current research is focused on evaluating the efficacy of low-dose, short-term lithium treatment to improve long bone fracture healing through a Phase II randomized clinical trial (LiFT NCT02999022). In working towards future applications of lithium for fracture management, this study aimed to understand the current perceptions of lithium as a psychiatric drug and the potential barriers to its orthopaedic adoption.

Methods

Three questionnaires, evaluating knowledge about lithium and willingness to embrace its use in fracture healing were disseminated among the general population, fracture patients eligible for the LiFT (Lithium for

SUBMITTER: Vachhani K 

PROVIDER: S-EPMC6717343 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature