Association between ADORA2A gene polymorphisms and schizophrenia in the North Chinese Han population.

ABSTRACT:

Background

A large number of studies have shown a close relationship between ADORA2A and the pathological mechanism of schizophrenia. However, to our knowledge, there has been no studies examining the association between the ADORA2A gene and schizophrenia in Chinese Han population.

Purpose

The objective of this study was to examine the relationship between adenosine A2A receptor (ADORA2A) single nucleotide polymorphisms and schizophrenia in the North Chinese Han population.

Patients and methods

We detected ADORA2A single nucleotide polymorphisms (SNPs) using polymerase chain reaction-restriction fragment length polymorphism analyses and summarized our results using SPSS statistical software and Haploview in schizophrenia case group (n=398)

SUBMITTER: Miao J 

PROVIDER: S-EPMC6718062 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature