Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster.

ABSTRACT: Learning and memory are critical functions for all animals, giving individuals the ability to respond to changes in their environment. Within populations, individuals vary, however the mechanisms underlying this variation in performance are largely unknown. Thus, it remains to be determined what genetic factors cause an individual to have high learning ability and what factors determine how well an individual will remember what they have learned. To genetically dissect learning and memory performance, we used the Drosophila synthetic population resource (DSPR), a multiparent mapping resource in the model system Drosophila melanogaster, consisting of a large set of recombinant inbred lines (RILs) that naturally vary in these and other traits. Fruit flies can be trained in a "heat box" to le

SUBMITTER: Williams-Simon PA 

PROVIDER: S-EPMC6718298 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature