Developing a prediction model for disease-free survival from upper urinary tract urothelial carcinoma in the Korean population.

ABSTRACT:

Background

In this study, we aimed to propose a validated prediction model for disease-free survival (DFS) after radical nephroureterectomy (RNU) in a Korean population with upper urinary tract urothelial carcinoma (UTUC).

Methods

We performed a retrospective review of 1561 cases of UTUC who underwent either open RNU (ONU, n = 906) or laparoscopic RNU (LNU, n = 615) from five tertiary Korean institutions between January 2000 and December 2012. Data were used to develop a prediction model using the Cox proportional hazards model. Prognostic factors were selected using the backward variable selection method. The prediction model performance was investigated using Harrell's concordance index (C-index) and Hosmer-Lemeshow type 2 statistics. Internal validation was performed usin

SUBMITTER: Kim SH 

PROVIDER: S-EPMC6718545 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature