Modeling the Interplay between Photosynthesis, CO₂ Fixation, and the Quinone Pool in a Purple Non-Sulfur Bacterium.

ABSTRACT: Rhodopseudomonas palustris CGA009 is a purple non-sulfur bacterium that can fix carbon dioxide (CO₂) and nitrogen or break down organic compounds for its carbon and nitrogen requirements. Light, inorganic, and organic compounds can all be used for its source of energy. Excess electrons produced during its metabolic processes can be exploited to produce hydrogen gas or biodegradable polyesters. A genome-scale metabolic model of the bacterium was reconstructed to study the interactions between photosynthesis, CO₂ fixation, and the redox state of the quinone pool. A comparison of model-predicted flux values with available Metabolic Flux Analysis (MFA) fluxes yielded predicted errors of 5-19% across four different growth substrates. The model predicted the presence of an

SUBMITTER: Alsiyabi A 

PROVIDER: S-EPMC6718658 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature