Defining the incremental value of 3D T2-weighted imaging in the assessment of prostate cancer extracapsular extension.

ABSTRACT:

Objectives

To assess the added value of 3D T2-weighted imaging (T2WI) over conventional 2D T2WI in diagnosing extracapsular extension (ECE).

Methods

Seventy-five patients undergoing 3-T MRI before radical prostatectomy were included. PI-RADS ≥ 4 lesions were assessed for ECE on 2D T2W images using a 5-point Likert scale (1 = no ECE, 5 = definite ECE) and the length of tumour prostatic capsular contact. A second read using 3D T2W images and reformats evaluated ECE and the maximal 3D capsular contact length and surface.

Results

One hundred six lesions were identified at MRI. ECE was confirmed by histology in 54% (57/106) of lesions and 64% (48/75) of patients. Sensitivity and specificity for 3D T2 reads were 75.4% versus 64.9% (p = 0.058), respectively, and 83.7% versus

SUBMITTER: Caglic I 

PROVIDER: S-EPMC6719333 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature