Gestational weight gain outside the Institute of Medicine recommendations and adverse pregnancy outcomes: analysis using individual participant data from randomised trials.

ABSTRACT:

Background

High Body Mass Index (BMI) and gestational weight gain (GWG) affect an increasing number of pregnancies. The Institute of Medicine (IOM) has issued recommendations on the optimal GWG for women according to their pre-pregnancy BMI (healthy, overweight or obese). It has been shown that pregnant women rarely met the recommendations; however, it is unclear by how much. Previous studies also adjusted the analyses for various women's characteristics making their comparison challenging.

Methods

We analysed individual participant data (IPD) of healthy women with a singleton pregnancy and a BMI of 18.5 kg/m² or more from the control arms of 36 randomised trials (16 countries). Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were used to describe the

SUBMITTER: Rogozinska E 

PROVIDER: S-EPMC6719382 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature