Associations of Mitochondrial Deoxyribonucleic Acid Polymorphisms With Behcet's Disease in the Korean Population.

ABSTRACT:

Objectives

This study aims to examine the possible associations of mitochondrial single nucleotide polymorphisms (SNPs) and Behçet's disease (BD) in a larger patient group.

Patients and methods

Whole blood or buffy coat was collected from 98 BD patients (31 males, 67 females; mean age 48±2.8 years; range 20 to 60 years) from four university hospitals located in the Chung-Cheong district of the Republic of Korea, and 196 age- and sex-matched healthy controls (HCs) (62 males, 134 females; mean age 46.91±12.90 years; range 20 to 68 years) from Konyang University Hospital. Twenty targeted mitochondrial deoxyribonucleic acids (DNAs) were genotyped and compared using the revised Cambridge Reference Sequence. Chi square and Fisher's exact tests were used to analyze association of m

SUBMITTER: Kwon M 

PROVIDER: S-EPMC6719587 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature