TACIT (High Sensitivity Troponin T Rules Out Acute Cardiac Insufficiency Trial).

ABSTRACT:

Background

Identifying low-risk acute heart failure patients safe for discharge from the emergency department is a major unmet need.

Methods and results

A prospective, observational, multicenter pilot study targeting lower risk acute heart failure patients to determine whether hsTnT (high-sensitivity troponin T) identifies emergency department acute heart failure patients at low risk for rehospitalization and mortality. hsTnT was drawn at baseline and 3 hours. Phone follow-up occurred at 30 and 90 days. The primary end point composite of all-cause mortality, rehospitalization, and emergency department visits at 90 days (changed from 30 days because of lack of mortality events), analyzed using logistic regression. Secondary end points: 30- and 90-day all-cause mortality. hsTn

SUBMITTER: Pang PS 

PROVIDER: S-EPMC6719714 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature