Balance of benefits and harms of different blood pressure targets in people with multiple chronic conditions: a quantitative benefit-harm assessment.

ABSTRACT:

Objective

Recent studies suggest that a systolic blood pressure (SBP) target of 120 mm Hg is appropriate for people with hypertension, but this is debated particularly in people with multiple chronic conditions (MCC). We aimed to quantitatively determine whether benefits of a lower SBP target justify increased risks of harm in people with MCC, considering patient-valued outcomes and their relative importance.

Design

Highly stratified quantitative benefit-harm assessment based on various input data identified as the most valid and applicable from a systematic review of evidence and based on weights from a patient preference survey.

Setting

Outpatient care.

Participants

Hypertensive patients, grouped by age, gender, prior history of stroke, chronic heart failure,

SUBMITTER: Aschmann HE 

PROVIDER: S-EPMC6720326 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature